DOK7 Antikörper
Kurzübersicht für DOK7 Antikörper (ABIN2719664)
Target
Alle DOK7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Produktmerkmale
- Homo sapiens docking protein 7 (DOK7), transcript variant 1
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Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
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Immunogen
- Full length human recombinant protein of human DOK7(NP_775931) produced in HEK293T cell.
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Isotyp
- IgG2b
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Applikationshinweise
- WB 1:2000, FLOW 1:100,
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Kommentare
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The concentration of the product may vary between diferrent lots.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5-1.0 mg/mL
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Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- DOK7 (Docking Protein 7 (DOK7))
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Andere Bezeichnung
- DOK7
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Hintergrund
- The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 52.9 kDa
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Gen-ID
- 285489
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NCBI Accession
- NM_173660
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HGNC
- 285489
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Pathways
- Skeletal Muscle Fiber Development
Target
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